Early Steps to Create a Synthetic, “Mirrored” Organism

The ribosome. Image courtesy of redondoself.
Figure: Schematic depicting the general mechanism of prokaryotic translation. The tRNA is acylated by its aminoacyl tRNA synthetase before being transported to the ribosome by EF-Tu. The ribosome adds the amino acid to the growing peptide chain following GTP hydrolysis and EF-Tu release. EF-G signals the ribosome via GTP hydrolysis to move one codon along the mRNA template, with the departure of the E-site tRNA. Images captured in PyMOL. PDB IDs: 4V5L, 3MF2, 2BM0.

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