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Niko McCarty
Niko McCarty

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Published in Codon

·Apr 18, 2022

Ancient Rubiscos, Resurrected

Proteins from Nightshade plants were expressed in E. coli, and could fix carbon dioxide faster than modern Rubisco. — Subscribe for free at codonmag.com. Hello. Ancient RuBisCOs are brought back to life in engineered bacteria. Chemical reprogramming shifts cells back to a pluripotent state. And a look at gut dysbiosis, and how to prevent it. Ancient Rubiscos Rubisco sucks. This protein behemoth takes carbon dioxide from the air and fixes it…

Science

3 min read

Ancient Rubiscos, Resurrected
Ancient Rubiscos, Resurrected
Science

3 min read


Published in Codon

·Apr 5, 2022

At Last, A Complete Human Genome

Plus: CRISPR’d cat cells & a supercharged prime editor to swap DNA bases. — Subscribe for free at codonmag.com. Hello. A complete human genome sequence adds a full chromosome’s worth of data to prior versions. An allergy-causing gene in cats is modified by CRISPR. And a tweak to prime editing boosts its efficiency by 353x, on average. The Human Genome Sequence is Complete About 8 percent of the human genome…

Tech

3 min read

At Last, A Complete Human Genome
At Last, A Complete Human Genome
Tech

3 min read


Published in Codon

·Apr 1, 2022

Microbial Cocoon Helps Cells Penetrate, Shrink Tumors

A tour-de-force in bacterial engineering for cancer therapy. — Subscribe for free at codonmag.com. Case Study Sometime in 1913, a patient walked through the doors of New York Hospital, the second oldest hospital in the United States, and met with Dr. William Coley, a bone surgeon. The patient’s concern was obvious: a large tumor — specifically, a sarcoma, a cancer that…

Tech

6 min read

Microbial Cocoon Helps Cells Penetrate, Shrink Tumors
Microbial Cocoon Helps Cells Penetrate, Shrink Tumors
Tech

6 min read


Published in Codon

·Apr 1, 2022

Extinct Christmas Island Rat Genome Sequenced; Plans for De-Extinction

The genome diverges just 4.85 percent from modern Norway brown rats. — Subscribe for free at codonmag.com. We have since built museums to celebrate the past, and spent decades studying prehistoric lives. And if all this has taught us anything, it is this: no species lasts forever. — Kenneth Branagh Woolly mammoth de-extinction efforts often grab headlines, while less conspicuous animals fly…

Tech

3 min read

Extinct Christmas Island Rat Genome Sequenced; Plans for De-Extinction
Extinct Christmas Island Rat Genome Sequenced; Plans for De-Extinction
Tech

3 min read


Published in Codon

·Apr 1, 2022

Electronics Meet Microbes: Tiny ‘Smart’ Pill Senses Gut Inflammation

By merging bio-ware and hardware, Tim Lu’s lab has developed a pill that can detect biomarkers of inflammatory bowel disease. — Subscribe for free at codonmag.com. All disease begins in the gut. — Hippocrates Hippocrates, writing more than two millennia ago, may have been on to something. In recent years, a scientific renaissance has cemented a link between the gut microbiome and myriad diseases, including Alzheimer’s.

Tech

5 min read

Electronics Meet Microbes: Tiny ‘Smart’ Pill Senses Gut Inflammation
Electronics Meet Microbes: Tiny ‘Smart’ Pill Senses Gut Inflammation
Tech

5 min read


Published in Codon

·Apr 1, 2022

Flexible CRISPR System & Ginkgo Earnings Call: Codon News #19

Plus: CRISPR’d cats & BigHat acquires Frugi Biotechnology, a cell-free diagnostics company. — Subscribe for free at codonmag.com Hello. In this issue, a Ginkgo earnings call reveals financial packages for top executives, biotech stocks are in decline & a more flexible CRISPR system could be used to correct a wide range of disease-causing genetic variants. Flexible CRISPR When correcting a faulty gene inside of a…

Tech

5 min read

Flexible CRISPR System & Ginkgo Earnings Call: Codon News #19
Flexible CRISPR System & Ginkgo Earnings Call: Codon News #19
Tech

5 min read


Published in Codon

·Mar 30, 2021

Cancer Therapy, Controlled with Sound

Cell Crunch (Issue 2021.03.30) — Reach out on Twitter with feedback and questions. Receive this free newsletter every Friday morning by clicking here. I have four tips: Curiosity … More curiosity. Even more curiosity. Passion. It’s not enough to be curious. — Ada Yonath All of the featured studies this week are preprints, and have…

Science

9 min read

Cancer Therapy, Controlled with Sound
Cancer Therapy, Controlled with Sound
Science

9 min read


Published in Codon

·Mar 28, 2021

Wagyu Beef, Grown in the Lab

Cell Crunch (Issue 2021.03.26) — Reach out on Twitter with feedback and questions. Receive this free newsletter every Friday morning by clicking here. By forces seemingly antagonistic and destructive Nature accomplishes her beneficent designs — now a flood of fire, now a flood of ice, now a flood of water; and again in the fullness…

Science

5 min read

Wagyu Beef, Grown in the Lab
Wagyu Beef, Grown in the Lab
Science

5 min read


Published in Codon

·Mar 22, 2021

“Aquaplastic” Made From Living Bacteria

Cell Crunch (Issue 2021.03.22) — Reach out on Twitter with feedback and questions. Receive this free newsletter every Friday morning by clicking here. Some paintings become famous because, being durable, they are viewed by successive generations, in each of which are likely to be found a few appreciative eyes. I know a painting so evanescent…

Science

8 min read

“Aquaplastic” Made From Living Bacteria
“Aquaplastic” Made From Living Bacteria
Science

8 min read


Published in Codon

·Mar 19, 2021

Embryo in a Mechanical Womb

Cell Crunch (Issue 2021.03.19) — Reach out on Twitter with feedback and questions. Receive this free newsletter every Friday morning by clicking here. You ask particularly after my health. I suppose that I have not many months to live; but, of course, I know nothing about it. …

Science

4 min read

Embryo in a Mechanical Womb
Embryo in a Mechanical Womb
Science

4 min read

Niko McCarty

Niko McCarty

335 Followers

Science journalism at NYU. Previously Caltech, Imperial College. #SynBio newsletter: https://synbio.substack.com Web: https://nikomccarty.com

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